As a key foundation of international trade, tourism, and investment, aviation is crucial to the global economy. This reliable, safe, and efficient transportation network carries over 2.6 billion passengers a year and 48 million tons of freight. Aviation’s global economic impact (direct, indirect, induced, and tourism catalytic) is estimated at $2.2 trillion or 3.5% of global gross domestic product (GDP). Disruption to this flow can result in significant economic and social disruption that would ripple across the globe, as demonstrated in the aftermath to the attacks of September 11, 2001. We now remain vigilant to adversaries who seek to disrupt the global economy by attacking aviation’s critical infrastructure.